N-(3-(8-cyano-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-ylamino)phenyl)acetamide

N-(3-(8-cyano–4–(phenylamino)pyrazolo[1,5-a][1,3,5]triazin–2–ylamino)phenyl)acetamide is a synthetic small molecule belonging to the acetanilides class. It is primarily characterized as a potent and selective inhibitor of casein kinase II subunit alpha (CK2α), an enzyme involved in various cellular processes including cell growth and survival. The compound has been studied experimentally for its binding affinity to CK2α with a reported Ki value of 0.35 nM. There are no approved therapeutic indications or marketed formulations; it remains an experimental research tool for probing CK2 biology and potential anti-neoplastic activity in preclinical settings.[2][4]

Other names

N-[3-{[8-cyano-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}phenyl]acetamideAcetamide,N-[3-{[8-cyano–4-(phenylamino)pyrazolo[1,5-a]-1,3,5-triazin–2–yl]amino}phenyl]